A new class of isoquinoline alkaloids: The indenobenzazepines

The dark yellow indenobenzazepine alkaloids lahorine ($\text{1}$) and lahoramine ($\text{2}$) have been found in $\text{Fumaria}$$\text{parviflora}$ Lam. (Fumariaceae). In a transformation with biogenetic implications, treatment of the spirobenzylisoquinolines dihydrofumariline ($\text{4}$) and dihydroparfumidine ($\text{7}$) with methanesulfonyl chloride and triethylamine in dry THF, followed by iodine oxidation, provided $\text{1}$ and $\text{2}$, respectively.     

CSE-MECC two-dimensional capillary electrophoresis analysis of proteins in the mouse tumor cell (AtT-20) homogenate

Two-dimensional capillary electrophoresis was used for the separation of proteins and biogenic amines from the mouse AtT-20 cell line. The first-dimension capillary contained a TRIS–CHES–SDS–dextran buffer to perform capillary sieving electrophoresis, which is based on molecular weight of proteins. The second-dimension capillary contained a TRIS–CHES–SDS buffer for micellar electrokinetic capillary chromatography. After a 61-s preliminary separation, fractions from the first-dimension capillary were successively transferred to the second-dimension capillary, where they further separated by MECC. The two-dimensional separation required 60 min.     

Calcined oyster shell nanoparticles (COS NPs): a new,efficient and reusable catalyst for one-pot rapid preparation of 1,8-dioxo-octahydroxanthenes under solvent-free conditions

Research on Chemical Intermediates - Calcined oyster shell nanoparticles (COS NPs) as a novel heterogeneous nanocatalyst were prepared and fully characterized by X-ray fluorescence analysis,...     

HEXAMETHYLDISILAZANE IN THE PRESENCE OF N,N′,N″,N‴-TETRAMETHYLTETRA-2,3-PYRIDINOPORPHYRAZINATO COPPER (II) IS A NEW,MILD AND HIGHLY EFFICIENT REAGENT FOR SILYLATION OF ALCOHOLS AND PHENOLS

Alcohols and phenols are protected with hexamethyldisilazane in the presence of N,N′,N′,N?-tetramethyletra-2,3-pyridinoporphyrazinato copper (II) in good-to-excellent yields at room temperature.     

Influence of hybrid nano-structures on thermal performance of shear rate dependent viscosity fluid over a heated rotating cone with Hall and ion slip currents

Journal of Thermal Analysis and Calorimetry - The fluid of shear rate dependent viscosity has totally different rheology and exhibits dynamics which play a key role in heat transfer rate and...     

Middle East respiratory syndrome coronavirus: transmission,virology and therapeutic targeting to aid in outbreak control

Middle East respiratory syndrome coronavirus (MERS-CoV) causes high fever, cough, acute respiratory tract infection and multiorgan dysfunction that may eventually lead to the death of the infected individuals. MERS-CoV is thought to be transmitted to humans through dromedary camels. The occurrence of the virus was first reported in the Middle East and it subsequently spread to several parts of the world. Since 2012, about 1368 infections, including ~487 deaths, have been reported worldwide. Notably, the recent human-to-human ‘superspreading'' of MERS-CoV in hospitals in South Korea has raised a major global health concern. The fatality rate in MERS-CoV infection is four times higher compared with that of the closely related severe acute respiratory syndrome coronavirus infection. Currently, no drug has been clinically approved to control MERS-CoV infection. In this study, we highlight the potential drug targets that can be used to develop anti-MERS-CoV therapeutics.     

Hypercomplex analysis and integration of systems of ordinary differential equations

We review the theory of hypercomplex numbers and hypercomplex analysis with the ultimate goal of applying them to issues related to the integration of systems of ordinary differential equations (ODEs). We introduce the notion of hypercomplexification, which allows the lifting of some results known for scalar ODEs to systems of ODEs. In particular, we provide another approach to the construction of superposition laws for some Riccati‐type systems, we obtain invariants of Abel‐type systems, we derive integrable Ermakov systems through hypercomplexification, we address the problem of linearization by hypercomplexification, and we provide a solution to the inverse problem of the calculus of variations for some systems of ODEs. Copyright © 2016 John Wiley & Sons, Ltd.     

EFFICIENT CONVERSION OF TETRAHYDROPYRANYL (THP) ETHERS TO THEIR CORRESPONDING CYANIDES WITH TRIPHENYLPHOSPHINE/2,3-DICHLORO- 5,6-DICYANOBENZOQUINONE/n-Bu4 NCN

Tetrahydropyranyl ethers were converted to their corresponding alkyl cyanides efficiently by using the triphenylphosphine/ 2,3-dichloro-5,6-dicyanobenoquinone/n-Bu ₄ NCN system in refluxing acetonitrile with good-to-excellent yields.